Cuzan Guest House is located in the Sian Ka'an Biosphere Reserve. Covering 1.5 million acres along the central coast of the State of Quintana Roo, the Sian Ka'an [Mayan for "Where the Sky Was Born"] was established in 1986 and included into UNESCO's list of natural world heritage sites in 1987. It is home to more than 330 species of birds. A rich variety of mammals and water creatures also inhabit the reserve. Cuzan Guest House provides a number of ways to explore the Sian Ka'an. Ascension Bay offers over 20 square miles of uniformly shallow water with its famous flats of white sand, marl and turtle grass. It's a wade fisher's dream with bonefish, permit, tarpon, ladyfish and barracuda.
- Tulum Naval Air Station (TUY) / 29.7 miles
- Cozumel International Airport (CZM) / 61.4 miles
- Playa del Carmen Airport (PCM) / 62.3 miles
* Not all airports listed here may be open to public use, or service commercial flights